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Inkey List Advanced Retinal Serum tube on a white background
Woman with visible signs of aging, showing product benefits on a white background.
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Skincare product with dual-retinoid complex and sirtalice on a white background
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Two skincare serum bottles with text describing starter and advanced retinol serums.
Before and after comparison of a skin treatment on a person's forehead.
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Advanced 0.05% Retinal Serum

Clinically proven to deliver anti-aging results 11x faster than standard retinol** - with visible improvements in just 1 week*

4.6
Rated 4.6 out of 5 stars
4.6 Stars (143 Reviews)
$30.00 / 15ml

What you get: A high-strength Retinal serum, clinically proven to target all 5 visible signs of aging, without irritation - smoothing deep wrinkles, fading dark spots, visibly firming and lifting while boosting skin’s luminosity. Perfect for experienced retinoid users ready to upgrade their anti-aging skincare routine.

Why it works: Formulated with 0.05% encapsulated Retinaldehyde, proven to work 11x faster than standard Retinol***, to accelerate cell turnover, promote collagen production and improve skin elasticity. Enhanced with 2% Sirtalice to visibly lift, tighten and smooth skin in as little as 30 minutes****. Unlike standard retinol serums that require multiple conversion steps, our retinaldehyde formula converts directly to retinoic acid in just one step - delivering faster, more effective anti-aging results.

How it feels: Lightweight, hydrating and fast-absorbing. Skin feels instantly nourished, never drying.

When to use: PM only, 2-3 nights a week to start. Increase frequency as your skin builds tolerance. Always follow with moisturizer and use SPF the next morning.


*** G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378

**** Clinical data from ingredient study

Suitable for:

  • Experienced retinoid users
  • All skin types

Targets:

  • Deep Wrinkles
  • Dark spots
  • Loss of firmness
  • Dullness

Awards & Features

Advanced Retinal Technology: The Next Level Beyond Retinol

Retinoids are the gold-standard for skin longevity - helping improve the look of wrinkles, dark spots and loss of firmness. This Advanced Retinal Serum is for experienced retinol users who want to level up results, without irritation.

  • Why it’s different: Retinal converts to active retinoic acid in one step, so it works 11x faster than standard retinol***. The formula pairs long-term skin renewal with instant firming.

  • What it does: 0.05% encapsulated retinal smooths wrinkles, refines texture and evens tone over time, while 2% Sirtalice™ delivers visible, surface-level firming in as little as 30 minutes**.

  • The results? Skin looks smoother, firmer, and brighter - from 1 week*

Shipping info

Standard tracked shipping

  • $6.99 or FREE on orders over $50. (2-8 business days)

No import duties or fees - Your order will ship domestically from our Canadian warehouse so you can shop with confidence knowing your order will arrive quickly without extra costs

*Find out more about shipping here.

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Have you tried?

This product

Advanced 0.05% Retinal Serum

Advanced 0.05% Retinal Serum

  • • For experienced retinoid users - ready to upgrade beyond standard retinol
  • • Works 11x faster than retinol*** - clinically proven visible results in just 1 week*
  • • 0.05% Retinal targets all 5 signs of aging - smooths deep wrinkles, fades dark spots, firms and lifts skin
  • • Advanced formula with instant benefits - includes Sirtalice™ for visible firming in 30 minutes**

or

Have you tried?

Starter Retinol Serum

Starter Retinol Serum

  • • Perfect for retinol beginners - gentle introduction to vitamin A skincare
  • • Sensitive skin friendly - smooths fine lines in 7 days without irritation*
  • • 0.01% Retinal formula - gently evens skin tone and refines texture
  • • Gradual cell renewal - builds tolerance while delivering visible improvements

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  • Before and after showing results of Advanced 0.05% Retinal Serum
  • Before and after showing results of Advanced 0.05% Retinal Serum
  • Before and after showing results of Advanced 0.05% Retinal Serum
  • Before and after showing results of Advanced 0.05% Retinal Serum
4.6
Rated 4.6 out of 5 stars
Based on 143 reviews
Total 5 star reviews: 111 Total 4 star reviews: 20 Total 3 star reviews: 6 Total 2 star reviews: 1 Total 1 star reviews: 5
Reviews Summary
Customers say this retinal serum has a lightweight, smooth texture that absorbs quickly without leaving residue. Many appreciate its gentle formula that doesn't cause irritation, dryness, or flaking like other retinal products. Users report seeing improvements in skin texture, brightness, and smoothness within weeks of use. The yellow-tinted serum layers well under moisturizers and leaves skin feeling soft and hydrated. Common feedback includes reduced appearance of fine lines, dark spots, and more even skin tone. While some mention the small tube size for the price, most find it effective and affordable compared to similar products. A few users didn't notice significant results after several weeks of use.
143 reviews
  • Erter P.
    Verified Buyer
    Reviewing
    Advanced 0.05% Retinal Serum Duo
    I recommend this product
    Age Range 35 - 44
    Skin Type Combination
    Skin Concerns Hyperpigmentation, Fine Lines and Wrinkles, Acne Scars
    Have you purchased an INKEY List product before? No
    How long have you used this product for? 1 month - 3 months
    Sensitive Skin Friendly? Yes
    Rated 5 out of 5 stars
    4 days ago
    It smoothes my wrinkles around my mounth and fprehead😄

    The serum significantly contributed to improving the texture and forehead wrinkles. It also reduced the size of my pores without overly drying out my skin. Impressive.

  • Vanessa L.
    Verified Buyer
    Reviewing
    Advanced 0.05% Retinal Serum
    I recommend this product
    Age Range 45 - 54
    Skin Type Dry
    Skin Concerns Dryness, Hyperpigmentation, Dull Skin
    Have you purchased an INKEY List product before? Yes
    How long have you used this product for? 3 months +
    Sensitive Skin Suitability I don’t have sensitive skin
    Rated 4 out of 5 stars
    6 days ago
    Great serum

    This stuff is great. My skin definitely looks brighter and it has tolerated the retinol level well

  • Barbara M.
    Verified Buyer
    Reviewing
    Advanced 0.05% Retinal Serum
    I recommend this product
    Age Range 65+
    Skin Type Combination
    Skin Concerns Damaged Skin Barrier, Fine Lines and Wrinkles, Texture
    Have you purchased an INKEY List product before? Yes
    How long have you used this product for? 1-3 weeks
    Sensitive Skin Suitability I don’t have sensitive skin
    Rated 5 out of 5 stars
    1 week ago
    Early but promising results

    At 70 , I’m grateful for anything that helps with my skin tone and although it’s early day , the results look very promising so far . I had no adverse reaction and my only slight peeve is - I wish the tube was slightly larger .